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Swallow the tablet whole with a full glass of water. Hepatic impairment (erectile dysfunction) canada cialis Of the total number of subjects in ED clinical studies of tadalafil, approximately 25 percent were 65 and over, while approximately 3 percent were 75 and over. Of the total number of subjects in BPH clinical studies of tadalafil (including the ED/BPH study), approximately 40 percent were over 65, while approximately 10 percent were 75 and over. In these clinical trials, no overall differences in efficacy or safety were observed between older (>65 and ≥75 years of age) and younger subjects (≤65 years of age). Therefore no dose adjustment is warranted based on age alone. However, a greater sensitivity to medications in some older individuals should be considered. [see Clinical Pharmacology (12.3)].

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The FDA's approval of Viagra (Sildenafil) on March 27, 1998[9] was a ground-breaking commercial event for the treatment of ED, with sales exceeding US$1 billion. Subsequently, the FDA approved Levitra (vardenafil) on August 19, 2003,[10] and Cialis (tadalafil) on November 21, 2003. sale levitra skin rashYour healthcare provider will tell you how much Viagra to take and when to take it. How to buy CIALIS

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